Description:
Kenpaullone is a potent inhibitor of CDK1/cyclin B (IC50 = 400 nM), CDK2/cyclin A (IC50 = 680 nM), CDK2/cyclin E (IC50 = 7.5 uM) and CDK5/p25 (IC50 = 850 nM). Kenpaullone inhibits CDK2/cyclin A, CDK2/cyclin E and CDK5/cyclin/p35 (IC50 values are 0.68, 7.5 and 0.85 μM respectively).
- Molecular Weight: 327.18
- Molecular Formula: C16H11BrN2O
Purity: 98%
Canonical SMILES:
C1C2=C(C3=CC=CC=C3NC1=O)NC4=C2C=C(C=C4)Br
InChI:
InChI=1S/C16H11BrN2O/c17-9-5-6-14-11(7-9)12-8-15(20)18-13-4-2-1-3-10(13)16(12)19-14/h1-7,19H,8H2,(H,18,20)
InChIKey: QQUXFYAWXPMDOE-UHFFFAOYSA-N
- Boiling Point: 613.0±45.0 °C at 760 mmHg
- Melting Point: >300°C (dec.)
- Appearance: Solid powder
- Application: Reprogramming
Synonyms:
NSC664704; NSC-664704; NSC 664704; 9-Bromopaullone; 1-azakenpaullone; Kenpaullone
More details are to be found on supplier website
